Incomplete Directed Perfect Phylogeny in linear time
Reconstructing the evolutionary history of a set of species is a central task in computational biology. In real data, it is often the case that some information is missing: the Incomplete Directed Perfect Phylogeny (IDPP) problem asks, given a collection of species described by a set of binary characters with some unknown states, to complete the missing states in such a way that the result can be explained with a directed perfect phylogeny. Pe’er et al. [SICOMP 2004] proposed a solution that takes O~ (nm) time (the O~ (· ) notation suppresses polylog factors) for n species and m characters. Their algorithm relies on pre-existing dynamic connectivity data structures: a computational study recently conducted by Fernández-Baca and Liu showed that, in this context, complex data structures perform worse than simpler ones with worse asymptotic bounds. This gives us the motivation to look into the particular properties of the dynamic connectivity problem in this setting, so as to avoid the use of sophisticated data structures as a blackbox. Not only are we successful in doing so, and give a much simpler O(nmlog n) -time algorithm for the IDPP problem; our insights into the specific structure of the problem lead to an asymptotically optimal O(nm) -time algorithm.
|Lecture Notes in Computer Science/Lecture Notes in Artificial Intelligence|
|Optimization for and with Machine Learning , Pan-genome Graph Algorithms and Data Integration|
|17th Algorithms and Data Structures Symposium|
|Organisation||Centrum Wiskunde & Informatica, Amsterdam, The Netherlands|
Bernardini, G, Bonizzoni, P, & Gawrychowski, P. (2021). Incomplete Directed Perfect Phylogeny in linear time. In Workshop on Algorithms and Data Structures (pp. 172–185). doi:10.1007/978-3-030-83508-8_13