Tomography is a widely used imaging tool to explore the 3D inner structure of object without having to cut it open using penetrating beams. In this talk, I will present the different aspects of tomographic imaging handled and developed at the Computational Imaging group in CWI, Amsterdam. The broad application range include cultural heritage imaging, food industry, biology and nanotechnologies. Some of these applications require specific treatment because of the imaging conditions (few projections, noise, setup geometry, etc.) and most of them need segmentation of the 3D images to extract the features of interest. In this context, some algorithmic tools developed within the group, with a focus on discrete tomography, will be presented.