In the project “statistical image analysis” of CWI we have studied some spatial point patterns that originated from biological observations. These observations were the positions of so called EGF‐receptors on the surface of human carcinoma cells. We propose a stochastic model for these point patterns. Since the EGF‐receptors appear in clusters on the cell surface, we have opted for the Poisson‐cluster‐process as the model. We estimated the three parameters in this process by means of a method described by Diggle. We also did some work in assessing the statistical reliability of our estimates. Copyright

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doi.org/10.1111/j.1467-9574.1991.tb01315.x
Statistica Neerlandica

Barendregt, L. G., & Rottschäfer, M. J. (1991). A Statistical analysis of spatial point patterns A case study. Statistica Neerlandica, 45(4), 345–363. doi:10.1111/j.1467-9574.1991.tb01315.x