X-ray computed tomography (CT) is a powerful tool for noninvasive cardiac imaging. However, radiation dose is a major issue. In this paper, we propose an iterative reconstruction method that reduces the radiation dose without compromising image quality. This is achieved by exploiting prior knowledge in two ways: the reconstructed object is assumed to consist of both stationary and dynamic regions over time and the dynamic region is assumed to have sparse structures after a proper sparsifying space-time transform. Experiments on simulation data and a real micro-CT cardiac mouse dataset show that, with comparable image quality, the radiation dose can be substantially reduced compared to conventional acquisition/reconstruction protocols.
Additional Metadata
Keywords cardiac CT, iterative reconstruction, region based SIRT, dynamic CT, 4D CT, dose reduction
THEME Life Sciences (theme 5)
Publisher IEEE
Stakeholder Unspecified
Persistent URL dx.doi.org/10.1109/ICIP.2015.7350770
Project Quantitative electron tomography by simultaneous parameter estimation and reconstruction
Conference IEEE International Conference on Image Processing
Van Eyndhoven, G, Batenburg, K.J, & Sijbers, J. (2015). Region-Based 4D Tomographic Image Reconstruction: Application to Cardiac X-ray CT. IEEE. doi:10.1109/ICIP.2015.7350770