X-ray computed tomography (CT) is a powerful tool for noninvasive cardiac imaging. However, radiation dose is a major issue. In this paper, we propose an iterative reconstruction method that reduces the radiation dose without compromising image quality. This is achieved by exploiting prior knowledge in two ways: the reconstructed object is assumed to consist of both stationary and dynamic regions over time and the dynamic region is assumed to have sparse structures after a proper sparsifying space-time transform. Experiments on simulation data and a real micro-CT cardiac mouse dataset show that, with comparable image quality, the radiation dose can be substantially reduced compared to conventional acquisition/reconstruction protocols.
cardiac CT, iterative reconstruction, region based SIRT, dynamic CT, 4D CT, dose reduction
Life Sciences (theme 5)
Quantitative electron tomography by simultaneous parameter estimation and reconstruction
IEEE International Conference on Image Processing
Scientific Computing

Van Eyndhoven, G, Batenburg, K.J, & Sijbers, J. (2015). Region-Based 4D Tomographic Image Reconstruction: Application to Cardiac X-ray CT. IEEE. doi:10.1109/ICIP.2015.7350770