Abstract
Recent experimental and theoretical studies suggest that crystallization and glass-like solidification are useful analogies for understanding cell ordering in confluent biological tissues. It remains unexplored how cellular ordering contributes to pattern formation during morphogenesis. With a computational model we show that a system of elongated, cohering biological cells can get dynamically arrested in a network pattern. Our model provides an explanation for the formation of cellular networks in culture systems that exclude intercellular interaction via chemotaxis or mechanical traction.
- Received 29 October 2012
DOI:https://doi.org/10.1103/PhysRevE.87.012725
©2013 American Physical Society